The key to winning the Final will be in creativity and finishing.
Creativity:
France - France is fielding the deepest squad of the entire World Cup. In Thuram and Gallas they have a defensive wall, then with added protection from Vieira and Makelele as holding midfielders. Abidal and Sagnol do a fine job on the sides, and their runs can be destructive alongside the hard-working Malouda. However, all of France's creativity lies in Zidane, Ribery, and Henry, and if they can turn on the heat like they did against Brazil, France looks set to be unstoppable.
Italy - Italy has had a big problem in midfield so far. Totti, acting as spearhead, has done relatively little, at least much less than what he is capable of. He has to step it up. Gattuso is Italy's Makelele, he will be extremely important protecting the defense and winning balls. As for Perrotta and Camoranesi, they give the ball away without much flair. What Italy has that France doesn't, however, is an Andrea Pirlo. This guy is danger. He has the abilities to exploit all of France's weaknesses - sharp passing, creativity, and above all, he knows how to shoot. Pirlo could also take advantage of Les Bleus' set-piece weakness.

Finishing: In a Final that will see very few scoring chances thanks to both teams' strong defending, it will be the team who can put away those chances that will come out victorious.
France - Thierry-ierry Henry. Although Titi consistently scores some 30 goals for Arsenal and has had an impressive World Cup tally, his ratio of shots to goals is not so good. Henry will definitely have to do better, and France is just hoping it won't be a repeat of his performance for Arsenal in the Champs League Final. Saha is suspended, but Trezeguet could come off the bench if the game exceeds 90 minutes. Judging from his performance against Togo, however, finishing looks to be a problem for France.
Italy - Luca Toni did relatively little against Germany. However, he was on fire against the Ukraine, and Italy's chances will depend on him. If Toni turns out to be out of form, however, Italy should definitely not play Iaquinta. What could really hurt France is Pippo Inzaghi. He is not only experienced, but also has that uncanny ability to be at the right time, right place, to score. If Fabien Barthez pulls another mistake like he did against Portugal, this could mean big trouble for France. Even Gregory Coupet has had the Inzaghi Experience. With Milan looking set to bow out of the Champions League Final against Lyon, Inzaghi pops up at the last minute and scores on a rebound. However, this will all depend on Marcelo Lippi's selection, and France may not have to worry about that threat.

Also....subs will be extremely important. Both teams are tired physically and mentally, and the choice of substitution might decide the outcome.
France - If Domenech subs-in Dhorasoo, Boumsong or Chimbonda I will absolutely kill myself. However, most likely to come-in are Wiltord, Govou, Trezeguet, or Silvestre. Italy must not be worried by Govou, he has been absolutely worthless. However, Wiltord could pose a threat, and Italy fans still remember Euro 2000.
Italy - It's Inzaghi. I don't think Daniele de Rossi, Iaquinta, or anyone else will help much.
 

Without Inzaghi, I am predicting France winning 2:1 just because I'm biased.
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With Inzaghi, the scoreline could be reversed.